Pathological Rupture of the Spleen in Uncomplicated Myeloma
نویسندگان
چکیده
Pathological rupture of the spleen in uncomplicated myeloma is extremely rare. We present a case of a splenic rupture which occurred in a 52 year old woman with uncomplicated multiple myeloma. The patient required an urgent splenectomy and had an uneventful recovery. Pathophysiological mechanisms leading to splenic rupture are discussed. Plasma cell leukaemias have been previously documented to present with splenic rupture. A subgroup of aggressive multiple myelomas such as in our case may have a similar tendency for splenic rupture.
منابع مشابه
Atraumatic Splenic Rupture Due to Ectopic Extramedullary Hematopoiesis after Autologous Stem Cell Transplantation in a Patient with AL Amyloidosis
A 50-year-old man was diagnosed with multiple myeloma complicating AL amyloidosis. Splenic rupture was complicated during autologous stem cell transplantation (auto-SCT). Granulocyte colony-stimulating factor (G-CSF) was not administered. A pathological examination of the spleen revealed that CD34-positive cells were concentrated in the ruptured part of the splenic capsule. Hematopoietic cells ...
متن کاملگزارش یک مورد پارگی طحال بدون سابقه ضربه در خانم باردار در بیمارستان شهید اکبرآبادیRupture of the Spleen without any History of Trauma in a Pregnant Woman in Shahid Akbar Abadi Hospital: A Case Report
Atraumatic rupture of the spleen is an uncommon but important clinical entity. Unfortunately, the diagnosis is often missed due to the absence of any history of trauma. Atraumatic rupture of the spleen has been described in the medical literature as a clinical oddity with grave consequences, if it is unrecognised and untreated. Clinical features of splenic rupture include pain, tenderness a...
متن کاملFatal splenic rupture caused by an atypical malignant lymphoma in a Holstein cow
Postmortem examination of a 5.5-year-old Holstein cow with history of sudden death showed a veryhuge spleen (120 × 45 × 10 cm) associated with severe haemoperitoneum. Histopathological findingsincluded extensive infiltration of medium to large sized lymphocytic and lymphoblastic cells with smallamounts of cytoplasm, round nuclei with coarsely granular chromatin in the spleen, and limited foci o...
متن کاملRuptured Spleen Following Laparoscopic Cholecystectomy
BACKGROUND Laparoscopic cholecystectomy is generally a safe and well-accepted procedure. However, in a small percentage of patients, it is associated with complications, such as bleeding and injury to the bile duct and other viscera. Splenic injury as a result of laparoscopic surgery has been reported only in the context of direct trauma, for example due to retraction in hand-assisted urologic ...
متن کاملSimple and Complicated Ruptures of the Intestines
II or 91*6 per cent, of these were uncomplicated with injuries to other internal organs, while 1 or 8"3 per cent, was accompanied with two superficial ruptures of the liver. Classification of the niptures of the intestines. ?As I did in the case of the ruptures of the liver and spleen, I propose to consider these cases also under two heads?those in which the only rupture was that of the intesti...
متن کامل